Purine nucleotides
Apexbio Technology LLC Adenosine 58-61-7 5g
Adenosine (CAS 58-61-7) is a purine nucleoside consisting of adenine covalently linked to a ribose sugar via a -N9-glycosidic bond Endogenously adenosine modulates cellular signaling through activation of specific G protein-coupled adenosine receptors (A1 A2A A2B and A3) influencing diverse physiological processes such as neurotransmission vasodilation and immune responses In biomedical research adenosine is widely utilized to investigate purinergic signaling pathways cardiac function and the regulation of inflammatory and neuroprotective mechanisms as well as serving as a pharmacological tool in receptor binding and functional assays
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5-triphosphate d
The product contains disodium salt crystals of ATP.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5'-triphosphate disodium salt hydrate Grade II, >=97% (HPLC), crystalline, from microbial | 34369-07-8 | MFCD00150755 | 10G
Adenosine 5'-triphosphate disodium salt hydrate Grade II, >=97% (HPLC), crystalline, from microbial | Purity: >=97% (HPLC) | 34369-07-8 | MFCD00150755 | 10G
Apexbio Technology LLC 2'-O-Methyl-N6-Methyl-ATP 100ul (100 mM)
2p-O-Methyl-N6-Methyl-ATP is a chemically modified ATP analog bearing methyl substitutions at the N6 position of adenine and the 2 -hydroxyl group of the ribose sugar 2p-O-Methyl-N6-Methyl-ATP is designed to facilitate the study of RNA methylation processes and RNA protein interactions supporting the mechanistic exploration of RNA-modifying enzymes and epigenetic regulatory pathways Based on these properties 2p-O-Methyl-N6-Methyl-ATP holds research potential in investigations of ligand RNA interactions and drug discovery applications targeting RNA-related biological processes
Abcam Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP), cyclic nucleotide second messenger, 1G
MW 367.19 Da, Purity >99%. Cyclic nucleotide second messenger derived from guanosine triphosphate. Generated by guanylate cyclases. Involved in a number of cellular processes; downstream targets include cyclic nucleotide gated channels, cGMP-regulated phosphodiesterases and cGMP-dependent kinases.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC LDE225 Diphosphate 1218778-77-8 50mg
LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 25mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Apexbio Technology LLC Adenosine 5-triphosphate 34369-07-8 100mg
Adenosine 5-triphosphate (ATP CAS 34369-07-8) also known as ATP disodium salt hydrate is a nucleotide central to cellular energy transfer It functions as the primary intracellular energy carrier undergoing hydrolysis to release energy required for numerous biochemical processes including muscle contraction signal transduction and biosynthetic reactions ATP also serves as a substrate for kinases in phosphorylation events and plays a regulatory role in purinergic signaling pathways In biomedical research ATP is widely used to study cellular metabolism enzyme activities and receptor-mediated responses
Apexbio Technology LLC Adenosine Kinase Inhibitor (hydrate) 10mg
Adenosine Kinase Inhibitor (hydrate) is a small-molecule inhibitor targeting adenosine kinase It is designed to inhibit adenosine kinase thereby regulating intracellular adenosine metabolism Adenosine Kinase Inhibitor (hydrate) exerts its biological activity primarily through selective enzyme inhibition In cell-free conditions Adenosine Kinase Inhibitor (hydrate) demonstrates potent inhibitory activity with an IC50 value of approximately 1 7 nM Based on these pharmacological properties Adenosine Kinase Inhibitor (hydrate) holds research potential in investigating pain perception mechanisms and inflammation modulation through adenosine signaling pathways
Cambridge Isotope Laboratories 5-FLUOROURIDINE 5-TRIPHOSPHATE
5000166180 5-FLUOROURIDINE 5-TRIPHOSPHATE